Actual Problems of Medicine and Pharmacy

QUERCETIN AS A POTENTIAL THERAPEUTIC AGENT IN HYPERTENSION COMPLICATED BY CONNECTIVE TISSUE DYSPLASIA

Yuriy Fedorov, Alona Kovpak, Volodymyr Pyndus, Sergіy Golota — Sat, 02 Nov 2024 00:00:00 +0000

This article summarizes data on the effect of quercetin during the treatment of arterial hypertension, complicated by connective tissue dysplasia. Currently, numerous studies are being conducted to study the role of various genes in the development of arterial hypertension. One of the risk factors for hypertension, which remains insufficiently studied, is collagen pathology - undifferentiated connective tissue dysplasia (UND). The presence of connective tissue in all organs and systems, its common origin with mesenchyme, smooth muscle, blood, and lymph leads to dysplastic changes in any organ and system. Among the many metabolic agents in the treatment of hypertension in combination with DST, the bioflavonoid quercetin, which has a pronounced antioxidant effect, deserves the most attention. The use of water-soluble quercetin in the complex therapy of patients with hypertension in combination with DST reduces the frequency of recurrence of hypertensive crises in the post-hospital period, reduces the number of complications, leads to a decrease in blood stabilization, pressure, additional hypotensive effect.

MODERN EDUCATIONAL ACTIVITY AIMED AT TRAINING HIGHLY QUALIFIED SPECIALISTS – DOCTORS AND PHARMACISTS, WHO ARE ABLE TO SOLVE PROFESSIONAL TASKS AND TAKE RESPONSIBILITY FOR THEIR SOLUTION IN THE SYSTEM OF LEGAL RELATIONS "DOCTOR-PATIENT-PHARMACIST"

Ihor Haiduchok, Olha Gumenyuk — Sat, 10 Aug 2024 00:00:00 +0000

WHO indicates that at least 140 countries recognize the right of citizens to health in their constitutions. Every citizen or patient deserves access to quality, timely and appropriate health care services without discrimination or financial hardship. The modern educational activity of the Lviv Medical University Medical University for the training of highly qualified specialists - doctors and pharmacists - was considered. It has been proven that graduates are able to solve professional tasks and take responsibility for solving them in the system of legal relations "doctor-patient-pharmacist". The improvement of the system of legal relations "doctor-patient-pharmacist" during the medical reform and the implementation of the Action Plan of the Cabinet of Ministers of Ukraine for self-realization, employment and active, responsible citizenship in accordance with the European educational space is analyzed. The priorities in the activities of the rectorate, deans, heads of departments, professors and teachers and teaching staff of the Lviv Medical University Medical University are given. The teaching of first aid in the conditions of hostilities, master classes in tactical medicine for students is outlined. The scientific results of the University's work are presented. Attention is focused on the organization and holding on November 14-15, 2024 of the XXI International multidisciplinary scientific and practical conference "Medical and pharmaceutical law of Ukraine: organization and economy of pharmaceutical and medical affairs, circulation of drugs, technology, safety, efficiency, quality control, general, judicial, evidence-based and clinical pharmacy and medicine, pharmacotherapy of health disorders" (Registration number of the Provider – No. 2102, in accordance with the Regulation on the system of continuous professional development of health care workers approved by the Resolution of the Cabinet of Ministers of Ukraine dated July 14, 2021 No. 725).

USAGE OF A SPECIAL SHAPE SCREWS FOR DIRECT ZIRCONIUM DIOXIDE SUPRASTRUCTURE FIXATION TO MULTI-UNIT ABUTMENTS WITHOUT THE USE OF A Ti-BASE PLATFORM

Fedir Shchepanskyi, Borys Shchepanskyi — Thu, 12 Dec 2024 00:00:00 +0000

Screw-retained implant-supported restorations, both single and full-arch, are becoming increasingly popular. These restorations prevent negative subgingival inflammation associated with cement residue by eliminating intraoral cementation of the restoration to the abutment. Traditionally, screw-retained restorations are cemented to Ti-base abutments in the laboratory and delivered to the clinician as such. The restoration may separate under function from the Ti-base it was luted to. Direct fixation of zirconia structures to multi-unit abutments using standard screws, although possible, is risky due to the design of the screws, which were designed to press the Ti-base platform, i.e., metal-to-metal contact, not zirconia. To eliminate these risks, one can use screws of a special shape, which allows safe and reliable direct fixation of the zirconia prosthesis to multi-unit abutments without the risk of its fracture at the point of contact with the abutment.

REHABILITATION OF PATIENTS WHO HAVE SUFFERED FACIAL NEURITIS

Nataliia Matsko — Mon, 09 Sep 2024 00:00:00 +0000

Modern interdisciplinary knowledge provided to medical students and pharmaceutical students during training, training, retraining and advanced training at the Lviv Medical University Medical University contributes to the highly qualified training of specialists who will soon enter the states or already work in health care institutions. I and pharmacies of different forms of ownership. In turn, the teaching staff of the department of physical therapy, occupational therapy, sports medicine and physical education consists of a team that includes peripheral nerve surgeons (plastic or facial plastic surgeon), family doctors, neurologists, otolaryngologists, ophthalmologists, physiotherapists and speech therapists. They collaborate with doctors of other specialties, pharmacists and lawyers, which is the guarantee of the most effective means of teaching the discipline at the modern level, as well as studying the level of providing holistic care to patients with facial paralysis. That is, we study and consider the assessment and treatment of facial nerve injuries. Emphasizes the role of the interprofessional team in the care of patients with facial nerve palsy undergoing facial nerve repair in a health care setting during outpatient or inpatient treatment. It should be noted that lesions of the facial nerve occur most often among the pathologies of the cranial nerves. They make up from 2 to 5% of all diseases of the peripheral nervous system of an inflammatory-degenerative nature and rank 1st in frequency among mononeuritis and mononeuropathies. In different regions of the world, the incidence of facial nerve neuritis ranges from 16.0 to 30.1 cases per 100,000 population. Our research was conducted in one of the Health Care Institution in Lviv. 20 patients with acute neuritis of the facial nerve were treated. Patients were divided into 2 subgroups of 10 people each. Group 1 patients received only medical treatment. Patients in group 2 were given non-medicated treatment (reflexology and hirudotherapy, buccal massage, seed therapy, passive-active exercises) along with medical treatment. Recovery of movement disorders in patients of group 2 occurred gradually from 5-6 days. 2-3 courses of 10 sessions were used. Contracture of the affected muscles was not observed. Methods of non-pharmacological treatment of acute neuritis of the facial nerve can significantly shorten the recovery process and prevent the development of facial muscle complications. The usual practice for neuritis of the facial nerve is to prescribe non-steroidal anti-inflammatory drugs that have anti-inflammatory and analgesic effects. In addition, painkillers may be prescribed. If the patient has severe pain and a high degree of nerve damage. The doctor may recommend, during pharmacotherapy, a short course of glucocorticosteroid drugs to relieve inflammation and alleviate the symptoms of the health disorder. At the same time, if it is established that the cause of neuritis is an infection (bacterium or virus), antibiotics or antiviral drugs are prescribed. In addition, when dry eyes appear, it is necessary to moisturize them with the help of special drops, and at night to cover the eyes with a bandage. The treatment does not require the patient to stay in a hospital, it can be carried out in an outpatient setting, under the supervision of a family doctor.

PHARMACY OF THE FUTURE: DEVELOPMENT OF THE THEMATIC IMPROVEMENT CYCLE "LATEST DISCOVERIES AND PROSPECTS IN THE FIELD OF PHARMACY"

Viktoriia Shapovalova, Alina Osyntseva, Nadiia Malekh, Valerii Shapovalov — Tue, 30 Jul 2024 00:00:00 +0000

The mass introduction of artificial intelligence into pharmaceutical science and medical technologies in the system of legal relations "doctor-patient-pharmacist" causes significant changes in the light of modern scientific discoveries and technological innovations. In order to ensure this, the successful implementation of the training program conducted by the Department of Pharmacy of the Faculty of Postgraduate Education of the Higher Private Educational Institution "Lviv Medical University" of the cycle of thematic improvement "Latest discoveries and prospects in the field of pharmacy" is required. This is an important step in the direction of continuous professional growth of specialists in the field of pharmacy. The relevance of the thematic improvement cycle is recognized as an important factor in supporting professional development in the pharmaceutical industry. Listeners of this cycle get the opportunity to familiarize themselves with the latest achievements and trends in pharmacy, which contributes to deepening their knowledge and understanding of modern challenges. The cycle contributes to the development of key competencies of specialists in the field of pharmacy, which is important for their successful professional activity. The use of innovative teaching methods, such as the Moodle platform, further emphasizes the importance of modernizing the educational process in accordance with modern requirements. At the same time, the cycle of thematic improvement stimulates the development of the sphere of health care and pharmacy. Contributes to increasing the level of professional competence of participants in the "doctor-patient-pharmacist" legal relationship. Improves the quality, timeliness and availability of personalized medical and pharmaceutical care. All these factors emphasize the importance and effectiveness of the cycle of thematic improvement, as well as its significant place in the modern system of postgraduate professional training and development of pharmacy.